Accutane FAQ

Accutane FAQ2022-05-23T19:31:57-06:00
Is there a Free version?2022-05-24T16:27:52-06:00

Yes, the essence of the course is presented here at no cost.

What is Accutane?2022-05-24T12:50:38-06:00

Isotretinoin, originally known for its brand name Accutane®, or Roaccutane® in parts of the world, was discovered in 1979 when it was first given to patients with severe acne, most of whom reacted with dramatic and permanent clearing of their acne symptoms. It is a vitamin A derivative (13-cis-retinoic acid) that is administered orally in pill form with a meal that contains an adequate amount of fat, normally for 15-20 weeks (3.5 – 4.5 months), although it is also sometimes prescribed at lower dosages for up to 6 months or longer. [1]

Accutane is an anti-cancer, chemotherapy drug. [2] The drug is also known as RoAccutane, Claravis, Sotret, Myorisan, Amnesteem, Absorica, or Isotretinoin.

Is Accutane really chemotherapy?2022-05-24T12:52:22-06:00

First of all, let’s look at the origin of the word chemotherapy in order to understand what it is:

Chemotherapy (n.): “treatment of diseases by chemical substances,” 1906, from German Chemotherapie, coined by German biochemist Paul Ehrlich (1854-1915), from chemo- + therapie. Especially of cancer from 1950s; short form chemo attested by 1977.

before vowels chem-, word-forming element denoting “relation to chemical action or chemicals,” from combining form of chemical (adj.), used to form scientific compound words from c. 1900. In 19c., chemico- was used.

therapy (n.)
1846, “medical treatment of disease,” from Modern Latin therapia, from Greek therapeia“curing, healing, service done to the sick; a waiting on, service,” from therapeuein “to cure, treat medically,” literally “attend, do service, take care of” (see therapeutic).

St. Jude Hospital tell us that:

Isotretinoin (Accutane) is a type of medicine drug called a retinoid. It acts on specific receptors of the cell nucleus to control cell growth. Isotretinoin may be used as a chemotherapy to treat certain types of cancer such as neuroblastoma. It is usually used as a treatment for severe acne. [1]

So, yes Accutane is a chemical substance used for the “medical treatment of disease”, namely cancer.

How does chemotherapy impact a person?2022-05-24T12:55:44-06:00

1. Introduction

The gastrointestinal (GI) tract harbors a complex community of bacteria, fungi, viruses, archaea, and their genomes, which affect human health and disease [1]. Dysbiosis, or a disruption of the gut microbiota, refers to adverse changes in the microbiota associated with disturbed homeostasis and disease [2]. Gut dysbiosis has been associated with behavioral changes and impaired immune function characterized by increased proinflammatory biomarkers in both humans and rodents [3,4,5]. Cancer treatments, notably chemotherapy, while lifesaving, have been associated with gut microbial dysbiosis [6,7,8]. Moreover, gut microbial associated changes in psychological and cognitive function following chemotherapy treatment have also been found [6,9,10]. Notably, while some of the studies discussed herein used techniques such as PICRUSt to infer the metabolic capacity of the microbiome, we focused our discussion of the findings from these studies on the taxonomic characterization of the microbiota using 16S rRNA sequencing, and, therefore, refer to microbiota throughout the manuscript as opposed

1.1. Chemotherapy Impacts the Gut Microbiota

The microbiota–gut–brain axis facilitates crosstalk between the microbiota and brain via neural, endocrine, immune and metabolic pathways [1,11], which are susceptible to chemotherapy-related toxicities. In a pre-clinical study with adult female mice, 6 cycles (i.e., one treatment per every other day) of paclitaxel chemotherapy altered gut microbiota composition, which was associated with changes in taxonomic relative abundance, colonic tissue integrity, and microglial activation [12]. In clinical studies, chemotherapy treatment has been shown to alter the gut microbiota. In a sample of 36 pediatric patients with acute lymphoblastic leukemia, stool samples collected at baseline and days 3 (mid-treatment) and 7 (immediately post-chemotherapy) showed that high-dose methotrexate chemotherapy significantly reduced the overall taxonomic abundance of the gut microbiota during treatment and relative to healthy controls [7]. Another study found that chemotherapy decreased abundance of microbes belonging to the Firmicutes phylum [8]. Moreover, chemotherapy-induced mucositis, a common GI symptom in patients undergoing chemotherapy, is associated with increased symptoms of pain, anxiety, and depression [13].

1.2. Chemotherapy Compromises the GI Tract

The microbiota–gut–brain axis influences immune function and behavior [14]. The epithelial layer that lines the GI tract is a fine-tuned interface between the host and the external environment. The epithelia’s paracellular permeability under healthy physiological conditions is tightly regulated by tight junction proteins that prevent passage of macromolecules [15]. Chemotherapy may compromise the protective epithelial layer in the gut [12]. Compromising this layer can lead to increased intestinal permeability (i.e., “leaky gut”), which will provide easy passage of bacteria and their byproducts, such as lipopolysaccharide (LPS), a bacterial endotoxin component of the cell wall of Gram-negative bacteria, from the gut lumen into the bloodstream [9,12,16]. A compromised gut can lead to an immune response, characterized by the expression of sickness behaviors (e.g., lethargy, anxiety, cognitive dysfunction)[17]. Chemotherapy has thus been implicated in increased intestinal wall permeability, mucositis, sickness behaviors, and changes in the gut microbiota [6,7,8,9,12]. However, it is unclear whether these adverse changes persist in the longer term after treatment has ended.

1.3. Chemotherapy Impacts Psychosocial Health

Chemotherapy is associated with acute and chronic adverse changes in psychosocial health, but potential underlying mechanisms require elucidation. Mental health, a dimension of psychosocial health (i.e., psychological, behavioral, emotional, and social factors), in this context, refers to one’s emotional, psychological, and social well-being [18]. A growing body of research implicates the gut microbiota in symptoms of anxiety and depression [16,19,20], post-traumatic stress disorder (PTSD) [21], fatigue [22,23], cognitive and social function, pain [1,24,25], and GI disturbance [26,27,28]. Moreover, changes in the gut microbiota have been associated with anxiety and depressive behaviors in animals and humans [16,29,30,31,32].Chemotherapy has been associated with cognitive and psychological impairments [9,33,34]. Many survivors of cancer have been treated with toxic anti-cancer therapies and face chronic physical and psychosocial challenges because of cancer and its treatments. During and after chemotherapy treatment, cognitive impairments (e.g., attention, concentration, processing speed) are reported [33]. Survivors also tend to report higher incidence of anxiety, depression, cancer-related fatigue, and other psychosocial symptoms compared to healthy peers [35,36]. However, potential underlying mechanisms that may contribute to the maintenance of psychosocial symptoms require clarification.

Although many cancer survivors face post-treatment challenges regardless of their age, young adults may face additional challenges and unmet needs [37,38]. Young adults may be particularly susceptible to psychosocial issues following a cancer experience due to the added stress of developmental challenges (e.g., finding a long-term partner, fertility concerns, career development, gaining financial stability) compared to older survivors [38,39]. Understanding potential chronic effects of cancer treatments on the gut microbiota, GI, and psychosocial outcomes, and how these factors may relate, is needed to improve cancer survivors’ wellbeing.

Can I take the course with a partner or other people?2022-05-10T15:44:04-06:00

Possibly. Paired course enrollments are available on the 1st and 15th of every month. Course participants will be paired by sex for safety reasons. If you are introduced to a fellow course participant, you are entirely responsible for your own safety. Contact me here to let me know you’d like to be paired.

Will this course help with anxiety?2022-05-10T15:45:28-06:00

There’s no guarantee, however the course does contain information that may help you reduce your anxiety.

Should I take this course as a prevention measure?2022-05-10T15:48:53-06:00

You can. The course is designed to support a strong foundation of physical, emotional, and mental health. The tools and methods you will learn in this course will help you to head off Accutane damage at the pass, so to speak. The sooner you address any (potentially hidden) disruptions caused by the drug, the better off your health will be for the rest of your life.

What about vitamin A toxicity?2022-05-24T12:59:32-06:00


As previously stated, Isotretinoin is a vitamin A derivative (13-cis-retinoic acid). Generally, signs of vitamin A toxicity are associated with long-term consumption of vitamin A in excess of 10 times the RDA (8,000-10,000 μg RAE/day or 25,000-33,000 IU/day). [1]

10 times the maximum RDA is 250,000 to 330,000 IUs.

What is a Typical Dosage of Isotretinoin?

The dosage of isotretinoin for acne treatment can start as low as 0.5 mg per kg of body weight per day (0.5 mg/kg/day) and it can go up to a high dosage of 2 mg per kg of body weight per day. And intermediate dosage also exists for one mg per kg. [2]

Conversion from Lbs to Kg

Low Dose: 0.5mg/kg/day

175lb person = 79.37kg = 132,283 IUs
130lb person = 58.96kg = 98,266IUs

Intermediate Dose: 1mg/kg/day

175lb person = 79.37kg = 264,566 IUs
130lb person = 58.96kg = 196,533 IUs

High Dose: 2mg/kg/day

175lb person = 79.37kg = 529,132 IUs
130lb person = 58.96kg = 393,066 IUs

Again, 10 times the maximum RDA is 250,000 to 330,000 IUs.

Can Accutane affect Thyroid Hormone, Vitamin D, and Steroids (e.g., estrogen)?2022-05-24T09:43:34-06:00

The activation of RAR by RA binding triggers the recruitment of transcriptional coregulators to target promoters, thereby inhibiting or allowing the transcription of genes (8). RXR also forms heterodimers with several other nuclear receptors, including thyroid hormone receptor (TR), vitamin D receptor (VDR), steroid receptors, and peroxisome proliferator-activated receptor (PPAR) (9). In this way, vitamin A may interact with thyroid hormone, vitamin D, steroids (e.g., estrogen), or PPAR ligands signaling pathways and influence the transcription of a broad range of genes.

By regulating the expression of over 500 retinoid-responsive genes (including several genes involved in vitamin A metabolism itself), retinoic acid isomers play major roles in cellular proliferation and differentiation (i.e., cell commitment to highly specialized functions).


Does Accutane cause joint pain?2022-05-24T09:45:25-06:00


The condition caused by vitamin A toxicity is called hypervitaminosis A. It is caused by overconsumption of preformed vitamin A, not carotenoids. Preformed vitamin A is rapidly absorbed and slowly cleared from the body. Therefore, toxicity from preformed vitamin A may result acutely from high-dose exposure over a short period of time or chronically from a much lower intake (2). Acute vitamin A toxicity is relatively rare, and symptoms include nausea, headache, fatigue, loss of appetite, dizziness, dry skin, desquamation, and cerebral edema. Signs of chronic toxicity include dry itchy skin, desquamation, anorexia, weight loss, headache, cerebral edema, enlarged liver, enlarged spleen, anemia, and bone and joint pain. Also, symptoms of vitamin A toxicity in infants include bulging fontanels. Severe cases of hypervitaminosis A may result in liver damage, hemorrhage, and coma. Generally, signs of toxicity are associated with long-term consumption of vitamin A in excess of 10 times the RDA (8,000-10,000 μg RAE/day or 25,000-33,000 IU/day). However, more research is necessary to determine if subclinical vitamin A toxicity is a concern in certain populations (89). There is evidence that some populations may be more susceptible to toxicity at lower doses, including the elderly, chronic alcohol users, and some people with a genetic predisposition to high cholesterol (90). In January 2001, the Food and Nutrition Board of the US Institute of Medicine set the tolerable upper intake level (UL) of vitamin A intake for adults at 3,000 μg RAE (10,000 IU)/day of preformed vitamin A (56).


I am a parent of a child who has taken Accutane. Can I take this course?2022-05-24T13:36:55-06:00

Yes, if your child is still a minor, I recommend taking the course together. Read the lessons together and then discuss them. You can support your child in following through on the actionable steps presented in each lesson. If your child prefers privacy, I can provide a separate login for you to study the material. At some point I will release a course just for parents of children who are struggling with accutane damage.

What does Accutane recovery look like?2022-05-24T13:37:31-06:00

In a nutshell, my accutane recovery has looked like: full nights of sleep, reliable physical and mental energy from morning till night, relief from depression and mood swings, a naturally positive outlook on life including a sense of joy and happiness every day, and a recovery of libido and life energy.

Are there payment options available?2022-05-24T13:38:43-06:00

You may purchase the course in stages.

Are there any additional costs associated with this course?2022-05-24T13:39:18-06:00

The course discusses various supplements and products which you may choose to purchase from third parties. Whether or not you choose to purchase these products, and from where, is up to you. I suggest having a budget of $600 to be spent over the course of 12 to 18 months as you try out various supplements and other solutions presented in the course.

Are you available to help me through the course?2022-05-24T13:39:59-06:00

The course is designed for you to be able to successfully walk the path to a vibrant recovery from accutane – using only the course materials. However, I am available as a practicing healer to support you along your journey. The cost of sessions is not included in the course. If the full course is purchased, I offer a reduced rate of $35/half hour for phone or video sessions. The regular rate is $150/hour.

Is this a video course?2022-05-24T13:40:29-06:00

No, the information is primarily presented as reading. Some of the lessons however, do have videos.

Why is this course so long? Isn’t there a simpler/faster way to get better?2022-05-24T13:41:05-06:00

Because accutane damage affects multiple systems in the body, a comprehensive approach is needed to ensure the best possible chance of a robust and lasting recovery. In my own recovery, there were several false dawns as I solved one part of the damage only to start suffering from another problem. Each time this happened, I didn’t understand what was going on. This course is designed to help you address the damage in an efficient, holistic way. Each stage of the course builds on the preceding ones. The intention is to support you in achieving the best possible health, that will last for the rest of your life.

This course seems like more than I need. Is there another option available?2022-05-24T13:41:52-06:00

Yes, you can schedule a consultation with me during which you can ask anything you like about your Accutane recovery. Note however that Accutane damage is complex by nature and the course is designed to cover all the bases. You might also consider taking the course in stages. Stages I & II have some very powerful lessons that may help you.

Can you say more about the cost of this course?2022-05-24T13:42:40-06:00

Yes. I decided to create this course as the most economical way to deliver the rather large body of information involved with Accutane recovery. For me to deliver all this information one on one at an hourly rate would take years of sessions and cost tens of thousands of dollars. With this course, the cost is reduced to $80 a month at the current sale price (assuming it takes 18 months to complete). As part of the course, I offer support sessions, if needed, at a significantly reduced rate of $35/half hour to course participants.

Personally, I would give anything to be able to go back in time and take a 1 to 2 year course that would’ve saved me decades of unnamed, undiagnosable suffering, depression, anxiety, and misery, and hundreds of thousands, or maybe even millions, of dollars in lost wages and income.

I’ve taken Accutane but I feel fine. Can I take this course as a preventative measure?2022-05-24T13:43:12-06:00

Absolutely. The course is designed to support a strong foundation of physical, emotional, and mental health. The tools and methods you will learn in this course will help you to head off Accutane damage at the pass, so to speak. The sooner you address any (potentially hidden) disruptions caused by the drug, the better off your health will be for the rest of your life.


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